Type 2 diabetes: a multifaceted disease
نویسندگان
چکیده
منابع مشابه
Type 2 diabetes as a redox disease.
Physical exercise has long been widely regarded as essential to human health. Yet, we do not know how exercise-stressed skeletal muscle cells that generate reactive oxygen species such as hydrogen peroxide (H2O2) delay—if not prevent—the occurrence and severity of diseases such as type 2 diabetes (as well as dementias, cardiovascular disease, and some cancers). Also unexplained is the recent fi...
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more than 2 million people in Canada and an estimated 150 million people around the world. Owing at least partly to the rising epidemic of obesity in most countries around the world, this number is expected to double by the year 2025. Diabetes is the seventh cause of death among Canadians, and the cost to society is expected to reach $15.6 billion by 2010.1 Most (90%) patients have type 2 DM, w...
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Background: Although studies reported diabetes mellitus screening cost effective, the mass screening for type2 diabetes remains controversial. In this study we reviewed the recently evidence about the cost effectiveness of mass screening systematically. Methods: We reviewed the MEDLINE, Scopus, Web of Science (WOS), and Cochrane library databases by MeSH terms to identify relevan...
متن کاملGenetics of Type 2 Diabetes- A Review Article
Objective: Type 2 diabetes (T2D) as a complex disease is the result of genetically heterogeneous factors and environmental issues interaction. Linkage and small-scale candidate gene studies were successful in identification of genetic susceptibilities of monogenic form of diseases. However, they were largely unsuccessful while applying to the more common forms of disease. By designing Genome Wi...
متن کاملA multifaceted school-based intervention to reduce risk for type 2 diabetes in at-risk youth.
OBJECTIVE To evaluate the impact of a multifaceted, school-based intervention on inner city youth at high risk for type 2 diabetes mellitus (T2DM) and to determine whether the addition of coping skills training (CST) and health coaching improves outcomes. METHOD 198 students in New Haven, CT at risk for T2DM (BMI>85th percentile and family history of diabetes) were randomized by school to an ...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2019
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-019-4909-y